2021 Indiana Preps Top25 Team Power Rankings | All Classes | ( ) indicates a previous ranking
| Team | Ranking | Prev. Ranking | W-L Record | |||
| Center Grove | 1 | 1 | 7-0 | |||
| Cathedral | 2 | 2 | 7-0 | |||
| Roncalli | 3 | 3 | 7-0 | |||
| Westfield | 4 | 4 | 6-1 | |||
| Merrillville | 5 | 5 | 7-0 | |||
| Carmel | 6 | 7 | 6-1 | |||
| Bishop Luers | 7 | 8 | 7-0 | |||
| Hamilton SE | 8 | 15 | 6-1 | |||
| West Lafayette | 9 | 12 | 7-0 | |||
| Brebeuf Jesuit | 10 | 9 | 6-1 | |||
| Leo | 11 | 16 | 7-0 | |||
| Decatur Central | 12 | 18 | 6-1 | |||
| Lawrence North | 13 | 22 | 6-1 | |||
| Gibson Southern | 14 | 14 | 6-1 | |||
| Brownsburg | 15 | 11 | 5-2 | |||
| Valparaiso | 16 | 6 | 6-1 | |||
| Chesterton | 17 | 17 | 6-1 | |||
| Warren Central | 18 | 10 | 5-2 | |||
| East Central | 19 | 19 | 6-1 | |||
| Andrean | 20 | 21 | 5-2 | |||
| Carroll | 21 | 24 | 6-1 | |||
| Indy Lutheran | 22 | 25 | 7-0 | |||
| Danville | 23 | 23 | 6-1 | |||
| Jasper | 24 | NR | 7-0 | |||
| Bloomington South | 25 | 13 | 6-1 | |||
| In Consideration: | ||||||
| Heritage Christian, Eastbrook, Lawrenceburg, Logansport, Mt. Vernon, Evansville Memorial | ||||||
| Dropped Out: | ||||||
| Mooresville | 20 | 20 | 5-2 |
